Search results for " Innovative"
showing 10 items of 89 documents
Anakinra drug retention rate and predictive factors of long-term response in systemic juvenile idiopathic arthritis and adult onset still disease
2019
Background and Objective: Only a few studies have reported long-term efficacy of interleukin (IL)-1 inhibition in systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still disease (AOSD). Herein we report on the effectiveness of anakinra (ANA), expressed in terms of drug retention rate (DRR), and evaluate the predictive factors of drug survival in a cohort of patients with sJIA and AOSD. Patients and Methods: This is a multicenter study reviewing retrospectively the medical records from 61 patients with sJIA and 76 with AOSD, all treated with ANA in 25 Italian tertiary referral centers. Results: The cumulative retention rate of ANA at 12-, 24-, 48-, and 60-month of follow-up was 7…
Stem Cells and Other Emerging Agents as Innovative "Drugs" in Neurodegenerative Diseases: Benefits and Limitations.
2018
The brain has a limited process of repair/regeneration linked to the restricted and localized activity of neuronal stem cells. Consequently, it shows a reduced capacity to counteract the age-related loss of neural and glial cells and to repair the consequent injuries/lesions of nervous system. This progressively determines nervous dysfunction and onset/progression of neurodegenerative diseases, which represent a serious social (and economic) problem of our populations. Thus, the research of efficient treatments is encouraged. Stem cell therapy might represent a solution. Today, it, indeed, represents the object of intensive research with the hope of using it, in a near future, as effective …
Editorial
2014
Environmentally Assessing Buildings Characterized by Complex Shape and Innovative Materials
2013
This paper addresses the emerging problem consisting in a correct energy and environmental evaluation of buildings belonging to the new architectural tendency. In fact, innovative buildings are often characterized by new materials that, not rarely, are not contemplated in current environmental databases. Moreover, unconventional shapes of these buildings could require further manufacturing processes that involve additional energy consumption not included in the commercial environmental database. Through the work a spotlighting of the problem is presented with reference to a real innovative building.
New Technologies for Adaptive Architecture
2019
Since the 1980s, the bioclimatic architecture has had the historical merit of having raised public and experts’ awareness on the importance of designing buildings with the purpose of solving the problem of energy saving. Nowadays, in the light of the most recent energy strategies policies, in force on an international and European scale, codified in EC Directive 31/2010 concerning the implementation of the Nearly Zer-Energy Buildings (NZEB), (Deru et al. 2006), the need for a new approach to redevelopment that focuses on environmental, climate and energy objectives with innovative technological solutions emerges, aimed at optimizing the passive bioclimatic behaviour of a building. In the wo…
Architettura emergenziale: buone pratiche esecutive
2022
This paper provides a comparative overview of different types of (temporary) shelters that have recently been used in various field locations in response to a forced displacement due to disastrous events. In particular, possible strategies useful to increase the sustainability of the humanitarian response and reduce the carbon footprint, while ensuring the adequacy and suitability of the shelters themselves, are here explored. This study investigates a systematic design framework that is often constrained by many obstacles such as the limited availability of low-cost materials, and a lack of local labour experience. To reduce the negative impact of a disaster, especially in the developing c…
Experiencing Artistic Innovativeness in Opera Shows
2022
A conceptual model of the impact of artistic innovativeness on consumption experience and satisfaction of opera shows
2020
Conférence en ligne; International audience
Adaptive Materials Research for Architecture
2018
The volume "Adaptive Materials Research for Architecture" is a Special Issue of the journal "Advanced Material Research". The goal of this volume is to spread knowledge on studies, analyses and results of scientific research carried out from academics, researchers, and scientists regarding the soundest issues related to smart materials, innovative technologies and ongoing researches in the field of adaptive materials in past and current architectural practice.
Character Education and Children’s Literature. An Opportunity to Experiment Innovative and Reflective Teaching.
2016
Discussion focuses on how literature can be brought into the curriculum in helping to develop character traits in a meaningful, substantial manner. The book examines also how using the flipped classroom model provides opportunities to design and deliver courses using active learning and engagement strategies to facilitate students’ teamwork, problem solving and critical thinking skills in a collegial environment.